Groups – Italy

Commissione di studio inter—regionale Forlì

The “Forlì” Commission named after the town where the first meeting was held, groups some 30 laboratories from Emilia-Romagna and other surrounding Italian region. The commission’s scientific secretariat is run by Dr. Gualtiero Pallotti (Ospedale Pierantoni – Forlì).

The characteristics of this first meeting organized together with Dr. Palloti, on 28th May in 1993 in Forlì, in response to requests received from the different parties, were atypical; in its aim to freely express doubts, problems, opinions, sensations, results and any other question related to the topic proposed.

Since its spontaneous constitution, the commission has held over a dozen meetings on the initial object argument of the study groups: assessment of methods to determine Free Light Chains (FLC) and Bence Jones Proteins (BJP) in urine.

The specific first results were published in Biochimica Clinica in 1995, vol. 19, n. 5, entitled “L’angolo dell’Elettroforesi” of F. Aguzzi with the title “Valutazione Multicentrica di metodi e protocolli per le Catene Leggere Libere e Proteine di Bence Jones in urine – Primi risultati”.

Subsequent results, obtained in joint experiments with other subsequently constituted commissions, were presented at different scientific society Meetings and Congresses; since the 1999 edition the commissions have been invited to present their results and conclusions at the CEFAR Courses “Proteins: from the Laboratory to the Clinic”.

Different meetings subsequent to the experiments have enabled the commission to formulate a draft on “Operational Recommendations” , which proposes some base characteristics the methods and protocols used for qualitative and quantitative BJP determination should comply with. Other conclusions drawn from the experiments and detail of the results obtained appear in the paragraph on results and conclusions.

Lately, at their recent meetings, the commission has been expanding the horizons of its experiments on applying the same methodology to proteinuria study in general. The objective, as initially for FCL and BJP, is to advance in the standardization of proteinuria study; by comparing traditional separative methods (EF, SDS, etc.) with dosing specific marker proteins in urine.

Commissione congiunta SIBioc/AIPAC/SIMEL, Sezioni Liguri

In 1997 the Ligure Sections of the SIBioC – AIPAC – SIMEL decided to commence in conjunction an analogous initiative to that of the “Forlì” Commission, also co-ordinated organizationally by NSC; and constituted the “Liguria” Commission, whose scientific secretariat is run by Dr. Liliana Burlando (già Ospedale Galliera – Genova) and Dr. Giovanna Zaninetta (Ospedale S. Martino – Genova), grouping some 14 laboratories in the area.

The “Liguria” commission has kept close contact with the other commissions, and particularly with the “Forlì” commission, leading them to present their results and conclusions jointly at different scientific society Meetings and Congresses, in particular those of SIBioC and the CEFAR courses.

The result of these discussion meetings after the experiments, has led the commission to formulate its own “Operational Recommendations“, whose base lines coincide with the “Forlì” commission document, complemented with two proposals:

  • considerations and mask for the report
  • quantitative determination assessment proposal

Both the “Forlì” and “Liguria” commissions are expanding their works to assessment of methods for the general study of proteinuria, to advance in their standardization.

Commissione di studio Lazio, Toscana/Umbria

Two new commissions were added to those of “Forlì” and “Liguria” in 2001, grouping between them some 30 laboratories from Lazio, Toscana and Umbria .

The “Lazio” Commission co-ordinated by Dr. Maria Teresa Muratore (Ospedale Civile – Viterbo), held their first meeting on 10th April 2001 in Vitorchiano, while the “Toscana-Umbría” Commission, whose scientific secretariat is run by Dr. Enzida Piazza (Ospedale Careggi – Firenze), was constituted on 24th May 2001.

The results and conclusions of their experiments were recently presented in conjunction with those of the “Forlì” and “Liguria” commissions, in the 2001 edition of the CEFAR Course (Castrocaro).