First article wich reports the study of the functionality of the method for determining FLCs by liquid-phase immunoprecipitation as a screening test in the study of Bence Jones proteinuria.

Exhibition of the presentation of the method at the congress on proteins held by the SIBioC (Italian Society of Clinical Biochemistry) in 1989.

Another article which studies the functionality of the method for determining FLCs as screening in the study of Bence Jones proteinuria.

Letter from L. Massaro to F. Aguzzi, coordinator of the protein section in the magazine of the SIBioC, in reply to his comments on the aforementioned article by Abate L., Martelli M. and Zannini R.

A case is reported in which the method for determining FLCs by liquid-phase immunoprecipitation, in this case in serum, is used to characterise the type of amyloidosis from which the patient suffered.

Poster presented at the 1991 congress of the SIBioC, showing the results obtained with the use of the method for determining the FLCs, automated in an APS nephelometer, as screening in the study of BJPs.

Another article in wich the application of the method for determining FLCs in the study of the BJPs is discussed.

Letter from L. Massaro to F. Aguzzi, coordinator of the protein section in the magazine of the SIBioC, which sets forth theoretical reflections on a subject of wide discussion at the time, the origin or cause of the electrophoretic pattern known as ladders.

Poster presented at the 1993 SEQC congress (Spanish Society of Clinical Chemistry) reporting the results obtained using the method to determine FLCs as Screening in the study of BJPs.

Another Poster, presented at the 1994 SEQC congress, reporting the results obtained using the method to determine FLCs as Screening in the study of BJPs.

This article reports the results obtained by the “Forli” Study Group in their first multicentric studies on methods and protocols usually used to study Bence Jones proteinuria.

Communication presented at the 1997 European Charcot Foundation congress, reporting the results obtained using the method to determine FLCs in cerebrospinal fluid in different neurological affections, particularly in Multiple Sclerosis.

Complete revision of the argument on the determination of Free Light Chains and Bence Jones proteins, with special emphasis on their physiopathology, theoretical aspects and problems of their determination and revision of available methods.
It includes a large bibliographical list.

Presentation of results obtained by the Study Groups “Forlì” and “Liguria”, in their studies on methods normally used in the study of BJP, at the joint Meeting of the SIBioC and CEFAR Course on proteins.
Further information on the results obtained by the Study Groups in their experiments can be found on the page referring to BJP Study Groups.

Presentation of the results obtained by the Study Groups “Forlì” and “Liguria”, in their studies on methods normally used in the study of BJP, at the joint Meeting of SIBioC and the CEFAR Course on proteins.
Further information, on results obtained by the Study Groups in their experiments, can be found on the page referring to BJP Study Groups.

Reports the study of the Free Kappa/Free Lambda index functionality as a screening method in the study of Bence Jones proteinuria, proposing for patients suspected of monoclonal gammapathy, the presentation of laboratory results in a single computerized report including preliminary visit data.

Reports the study of nephelometric FLC determination functionality as a Screening method in the study of Bence Jones proteinuria, making an exhaustive comparison with Immunofixation taken as a reference method.
It includes a complete study of the nephelometric method performances and characteristics for FLC determination.

Joint presentation of results obtained by the different Italian Study Groups in their studies on the methods usually used in the study of BJP.
Further information, on the results obtained by the Study Groups in their experiments, can be found on the page referring to the BJP Study Groups.

Via a retrospective study of the hospital archives, the convenience/need to use anti Free Light Chains antisera in urinary Immunofixation is revised and discussed.

Study of the capacity of different methods to detect monoclonal and polyclonal FLCs in urine.

Explanation and revision of the concept on the use of specific protein markers in the study of proteinuria and presentation of the Software “MDI-LabLink” enabling its computerization.

Study of the effectiveness of using the FLC nephelometric measurement as Screening method to detect Bence Jones proteinuria.

Study of the Immunofixation method sensitivity used in the study of BJP in various groups of patients classified according their FLC concentration nephelometrically measured.

Study of the effectiveness of using the nephelometric measurement of FLC as a Screening method to detect the Bence Jones proteinuria.

Reports the study on the functionality of the FLC nephelometric determination as a Screening method in the study of Bence Jones proteinuria making an exhaustive comparison with the Immunofixation taken as the reference method.
To highlight the focus novelty, centered on improving the quality of the process and final result obtained (in the study of Bence Jones proteinuria) provided by the use of nephelometry as a Screening method

Assessment of the Free Light Chain measurement nephelometric method performances and evaluation of its use as screening method in the study of the Bence Jones proteinuria.

Complete revision of the argument on the determination of Free Light Chains and Bence Jones proteins, with special emphasis on their physiopathology, theoretical aspects and problems of their determination and revision of available methods.
It includes a large bibliographical list.

Presentation of the NSC´s Free Light Chain kits.

Proposal of operative protocol based on the use of liquid-phase immunoprecipitation (nephelometry or turbidimetry) as a first-level test, indicative of the presence of free light chains (FLCs), followed up by immunofixation as a confirmation test, to determine whether or not the FLCs present are monoclonal, i.e. Bence Jones (BJP).

Revision of the typical urinary immunofixation patterns found in the BJP study.